Ligand substituent effect on the cytotoxicity activity of two new copper(ii) complexes bearing 8-hydroxyquinoline derivatives: validated by MTT assay and apoptosis in MCF-7 cancer cell line (human breast cancer)-Reference-Cited by-同舟云学术

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Ligand substituent effect on the cytotoxicity activity of two new copper(ii) complexes bearing 8-hydroxyquinoline derivatives: validated by MTT assay and apoptosis in MCF-7 cancer cell line (human breast cancer)

Published:2021 Issue:24 Volume:11 Page:14362-14373
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Ali Arif¹²³⁴⁵,Banerjee Somesh⁶⁷⁸⁹¹⁰,Kamaal Saima¹²³⁴⁵,Usman Mohammad¹¹¹²¹⁰,Das Neeladrisingha⁶⁷⁸⁹¹⁰,Afzal Mohd¹¹¹³¹⁴¹⁵¹⁶^ORCID,Alarifi Abdullah¹¹¹³¹⁴¹⁵¹⁶,Sepay Nayim¹¹¹⁷¹⁸¹⁰^ORCID,Roy Partha⁶⁷⁸⁹¹⁰,Ahmad Musheer¹²³⁴⁵^ORCID

Affiliation:

1. Department of Applied Chemistry

2. ZHCET

3. Faculty of Engineering and Technology

4. Aligarh Muslim University

5. Aligarh–202002

6. Molecular Endocrinology Laboratory

7. Department of Biotechnology

8. Indian Institute of Technology Roorkee

9. Roorkee

10. India

11. Department of Chemistry

12. IIT Kanpur

13. College of Science

14. King Saud University

15. Riyadh–11451

16. Saudi Arabia

17. Lady Brabourne College

18. Kolkata–700 017

Abstract

The presence of –COOH functionality in a copper(ii) complex leads to higher cytotoxicity than that observed for a complex containing a –CN group.

Funder

Aligarh Muslim University

King Saud University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/RA/D1RA00172H

Reference54 articles.

1. Recent advances in the synthesis of biologically and pharmaceutically active quinoline and its analogues: a review

2. Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model

3. New quinoline/chalcone hybrids as anti-cancer agents: Design, synthesis, and evaluations of cytotoxicity and PI3K inhibitory activity

4. Comprehensive review on current developments of quinoline-based anticancer agents

5. Studies on antitumor mechanism of two planar platinum(II) complexes with 8-hydroxyquinoline: Synthesis, characterization, cytotoxicity, cell cycle and apoptosis

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