Development of a FRET-based recombinant tension sensor to visualize cell–material interactions

Author:

Kambe Yusuke1234,Kojima Katsura5674,Tomita Naohide89101112,Tamada Yasushi1314154,Yamaoka Tetsuji1234

Affiliation:

1. Department of Biomedical Engineering

2. National Cerebral and Cardiovascular Center Research Institute

3. Suita

4. Japan

5. Silk Materials Research Unit

6. National Institute of Agrobiological Sciences

7. Tsukuba

8. Department of Mechanical Engineering and Science

9. Graduate School of Engineering

10. Kyoto University

11. Kyoto-Daigaku-Katsura

12. Kyoto 615-8540

13. Faculty of Textile Science and Technology

14. Shinshu University

15. Ueda

Abstract

A recombinant tension sensor immobilized to a surface enables the real-time visualization of cell traction force at the focal adhesion level.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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