Stereoselective three-component cascade synthesis of α-substituted 2,4-dienamides from gem-difluorochloro ethanes-Reference-Cited by-同舟云学术

Stereoselective three-component cascade synthesis of α-substituted 2,4-dienamides from gem-difluorochloro ethanes

Published:2019 Issue:95 Volume:55 Page:14355-14358
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Das Shyamsundar¹²³⁴⁵,Ko Nakeun⁶⁷⁸⁵,Lee Eunsung⁶⁷⁸⁵^ORCID,Kim Sang Eun¹²³⁴⁵,Lee Byung Chul¹²³⁴⁵^ORCID

Affiliation:

1. Department of Nuclear Medicine

2. Seoul National University College of Medicine

3. Seoul National University Bundang Hospital

4. Seongnam

5. Republic of Korea

6. Department of Chemistry

7. Pohang University of Science and Technology

8. Pohang

Abstract

Herein, we describe a new transition metal-free Claisen rearrangement for the synthesis of α-substituted 2,4-dienamide. This one-pot, stereoselective three-component cascade reaction affords various polysubstituted 2,4-dienamides in good yields.

Funder

National Research Foundation of Korea

Korea Health Industry Development Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CC/C9CC07100H

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