A disulfide molecule–vancomycin nanodrug delivery system efficiently eradicates intracellular bacteria-Reference-Cited by-同舟云学术

A disulfide molecule–vancomycin nanodrug delivery system efficiently eradicates intracellular bacteria

Published:2024 Issue:9 Volume:12 Page:2334-2345
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Luo Yuting¹,Su Liu²,Yang Hui¹,Geng Aizhen²,Bai Shumeng²^ORCID,Zhou Jie¹³

Affiliation:

1. MOE Key Laboratory for Analytical Science of Food Safety and Biology, College of Chemistry, Fuzhou University, Fuzhou, Fujian 350108, China

2. College of Biological Science and Engineering, Fuzhou University, Fuzhou, Fujian 350108, China

3. China Fujian Key Laboratory of Drug Target Discovery and Structural and Functional Research, The School of Pharmacy, Fujian Medical University, Fuzhou, 350122, China

Abstract

A thiol-mediated nanodrug delivery system was developed to improve the cell membrane penetration efficiency and intracellular antibacterial activities of antibiotics.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Fujian Medical University

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/TB/D3TB02430J

Reference57 articles.

1. Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

2. Dual therapeutic targeting of intra-articular inflammation and intracellular bacteria enhances chondroprotection in septic arthritis

3. Intracellular Staphylococcus aureus persisters upon antibiotic exposure

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