Digging into protein metalation differences triggered by fluorine containing-dirhodium tetracarboxylate analogues

Author:

Loreto Domenico1ORCID,Esposito Anna2ORCID,Demitri Nicola3ORCID,Guaragna Annalisa2ORCID,Merlino Antonello1ORCID

Affiliation:

1. Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte Sant'Angelo, via Cinthia 21, 80126 Naples, Italy

2. Department of Chemical, Materials and Production Engineering, University of Naples Federico II, P.le V. Tecchio 80, 80125 Naples, Italy

3. Elettra–Sincrotrone Trieste, S.S. 14 km 163.5 in Area Science Park, 34149 Trieste, Italy

Abstract

The interaction of [Rh2(OAc)(tfa)3] with RNase A and HEWL was investigated in solution and at solid state. The results indicate that [Rh2(OAc)(tfa)3] reacts with proteins differently from [Rh2(OAc)4] and [cis-Rh2(OAc)2(tfa)2].

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

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