Potential of desorption electrospray ionization and paper spray ionization with high-resolution mass spectrometry for the screening of sports doping agents in urine

Author:

Bressan Claudia1ORCID,Seró Raquel2,Alechaga Élida13ORCID,Monfort Nuria1,Moyano Encarnación2ORCID,Ventura Rosa1

Affiliation:

1. Catalonian Antidoping Laboratory, Doping Control Research Group, IMIM (Hospital del Mar Medical Research Institute), Doctor Aiguader 88, 08003 Barcelona, Spain

2. Department of Chemical Engineering and Analytical Chemistry, University of Barcelona, Av. Diagonal 645, 08028 Barcelona, Spain

3. Department of Experimental and Health Sciences, Universitat Pompeu Fabra, Doctor Aiguader 88, 08003 Barcelona, Spain

Abstract

In this work, desorption electrospray ionization and paper spray ionization both with high-resolution mass spectrometry (DESI-HRMS and PSI-HRMS) were explored for the fast and direct analysis of stimulants and diuretics in urine samples.

Funder

Ministerio de Economía y Competitividad

Ministerio de Ciencia, Innovación y Universidades

Generalitat de Catalunya

Agència de Gestió d'Ajuts Universitaris i de Recerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Reference51 articles.

1. International Standard for Laboratories , World Anti-Doping Agency , 2021 , https://www.wada-ama.org

2. WADA Technical Document – TD2022MRPL , World Anti-Doping Agency , 2022 , https://www.wada-ama.org

3. The Prohibited List , World Anti-Doping Agency , 2022 , https://www.wada-ama.org

4. High-throughput screening for various classes of doping agents using a new ‘dilute-and-shoot’ liquid chromatography-tandem mass spectrometry multi-target approach

5. Liquid Chromatography-Tandem Mass Spectrometry Screening Method for the Simultaneous Detection of Stimulants and Diuretics in Urine

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