Chlorogenic acid ameliorates Klebsiella pneumoniae-induced pneumonia in immunosuppressed mice via inhibiting the activation of NLRP3 inflammasomes-Reference-Cited by-同舟云学术

Chlorogenic acid ameliorates Klebsiella pneumoniae-induced pneumonia in immunosuppressed mice via inhibiting the activation of NLRP3 inflammasomes

Published:2021 Issue:19 Volume:12 Page:9466-9475
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Zeng Junhao¹²,Wan Xiaoyu¹²,Liu Ting¹,Xiong Ying¹,Xiang Gan¹,Peng Yali¹,Zhu Ronghua¹,Zhou Yongqin¹²³,Liu Chaoqi¹²^ORCID

Affiliation:

1. College of Medical Science, China Three Gorges University, Yichang, Hubei, 443000, China

2. Hubei Key Laboratory of Tumor Microenvironment and Immunotherapy, Yichang, Hubei, 443000, China

3. The Institute of Infection and Inflammation, China Three Gorges University, Yichang, Hubei, 443000, China

Abstract

Utilizing the inflammatory response models both in vivo and in vitro, we demonstrated that the dietary intake of chlorogenic acid ameliorated K. pneumonia-induced pneumonia via inhibiting the activation of the NLRP3 inflammasome.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Hubei Province

China Three Gorges University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2021/FO/D0FO03185B

Reference42 articles.

Protective Effects of Chlorogenic Acid on Cerebral Ischemia/Reperfusion Injury Rats by Regulating Oxidative Stress-Related Nrf2 Pathway

2. Tyrosinase Inhibition Antioxidant Effect and Cytotoxicity Studies of the Extracts of Cudrania tricuspidata Fruit Standardized in Chlorogenic Acid

3. Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial

4. Chlorogenic acid (CGA): A pharmacological review and call for further research

5. Increased ROS Scavenging and Antioxidant Efficiency of Chlorogenic Acid Compound Delivered via a Chitosan Nanoparticulate System for Efficient In Vitro Visualization and Accumulation in Human Renal Adenocarcinoma Cells

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