Low levels of lipid oxidation radically increase the passive permeability of lipid bilayers
Author:
Affiliation:
1. Mork Family Department of Chemical Engineering and Materials Science
2. University of Southern California
3. Los Angeles, USA
Abstract
In a model lipid bilayer system with well-controlled concentrations of an oxidized lipid species, small amounts of lipid oxidation lead to large increases in small-molecule permeability.
Publisher
Royal Society of Chemistry (RSC)
Subject
Condensed Matter Physics,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SM/C4SM01478B
Reference41 articles.
1. Asymmetric Oxidation of Giant Vesicles Triggers Curvature-Associated Shape Transition and Permeabilization
2. Giant Vesicles under Oxidative Stress Induced by a Membrane-Anchored Photosensitizer
3. The dynamics of giant unilamellar vesicle oxidation probed by morphological transitions
4. Oxidation of unsaturated phospholipids in membrane bilayer mixtures is accompanied by membrane fluidity changes
5. Oxidized Phosphatidylcholines Promote Phase Separation of Cholesterol-Sphingomyelin Domains
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