Development of a fluorescent nanoprobe based on an amphiphilic single-benzene-based fluorophore for lipid droplet detection and its practical applications

Author:

Jung Yuna1,Jin Ji Hye1,Kim Youngseo2,Oh Ji Hyeon1ORCID,Moon Heechang3ORCID,Jeong Huisu3,Kim Jaehoon1ORCID,Park Yoon Kyung1,Oh Yohan34,Park Sungnam2ORCID,Kim Dokyoung15678ORCID

Affiliation:

1. Department of Biomedical Science, Graduate School, Kyung Hee University, Seoul 02447, Republic of Korea

2. Department of Chemistry, Korea University, Seoul, 02841, Republic of Korea

3. Department of Biomedical Science, Graduate School of Biomedical Science and Engineering, Hanyang University, Seoul 04763, Korea

4. Department of Biochemistry and Molecular Biology, College of Medicine, Hanyang University, Seoul 04763, Korea

5. Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical Science Institute, Kyung Hee University, Seoul 02447, Republic of Korea

6. Department of Anatomy and Neurobiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea

7. Center for Converging Humanities, Kyung Hee University, Seoul 02447, Republic of Korea

8. KHU-KIST Department of Converging Science and Technology, Kyung Hee University, Seoul 02447, Republic of Korea

Abstract

A new fluorescent nanoprobe based on a single-benzene-based fluorophore is developed for the detection and bioimaging of lipid droplets and applied in the visualization of fingerprints.

Funder

National Research Foundation of Korea

Korea Health Industry Development Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

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