Dietary Vitamin K1 intake is associated with lower long-term fracture-related hospitalization risk: the Perth longitudinal study of ageing women

Author:

Sim Marc123ORCID,Strydom Andre2,Blekkenhorst Lauren C.123,Bondonno Nicola P.14ORCID,McCormick Rachel1,Lim Wai H.25,Zhu Kun26,Byrnes Elizabeth7,Hodgson Jonathan M.123,Lewis Joshua R.1238,Prince Richard L.129

Affiliation:

1. Nutrition & Health Innovation Research Institute, School of Health and Medical Sciences, Edith Cowan University, Perth, Western Australia, Australia

2. Medical School, The University of Western Australia, Perth, Western Australia, Australia

3. Royal Perth Hospital Research Foundation, Perth, Western Australia, Australia

4. Danish Cancer Society, Copenhagen, Denmark

5. Department of Renal Medicine, Sir Charles Gairdner Hospital, Perth, Australia

6. Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, Australia

7. Department of Clinical Biochemistry, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Perth, Australia

8. Centre for Kidney Research, Children's Hospital at Westmead, School of Public Health, Sydney Medical School, The University of Sydney, Sydney, New South Wales, Australia

9. Curtin University, School of Public Health, Perth, Western Australia, Australia

Abstract

In multivariable-adjusted models including plasma Vitamin D, higher dietary Vitamin K1 (∼≥100 μg d−1) was associated with lower risk for any fracture (A) and hip fracture-related hospitalizations (B) over 14.5 years in community-dwelling older women.

Funder

Department of Health, Australian Government

Royal Perth Hospital Medical Research Foundation

National Health and Medical Research Council

National Heart Foundation of Australia

Healthway

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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