Degradable polymer prodrugs with adjustable activity from drug-initiated radical ring-opening copolymerization-Reference-Cited by-同舟云学术

Degradable polymer prodrugs with adjustable activity from drug-initiated radical ring-opening copolymerization

Published:2018 Issue:43 Volume:9 Page:8291-8306
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Guégain Elise¹²³⁴⁵^ORCID,Tran Johanna¹²³⁴⁵^ORCID,Deguettes Quentin¹²³⁴⁵,Nicolas Julien¹²³⁴⁵^ORCID

Affiliation:

1. Institut Galien Paris-Sud

2. CNRS UMR 8612

3. Univ Paris-Sud

4. Faculté de Pharmacie

5. France

Abstract

Degradable polymer prodrugs were synthesized by ‘drug-initiated’ nitroxide-mediated radical ring-opening copolymerization and led to either nanoparticles or soluble prodrugs with adjustable cytotoxicity on two different cancer cell lines.

Funder

Agence Nationale de la Recherche

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/SC/C8SC02256A

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5. Paclitaxel-Initiated, Controlled Polymerization of Lactide for the Formulation of Polymeric Nanoparticulate Delivery Vehicles

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