Cell-derived extracellular vesicles for CRISPR/Cas9 delivery: engineering strategies for cargo packaging and loading-Reference-Cited by-同舟云学术

Cell-derived extracellular vesicles for CRISPR/Cas9 delivery: engineering strategies for cargo packaging and loading

Published:2022 Issue:15 Volume:10 Page:4095-4106
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Liang Yujie¹^ORCID,Iqbal Zoya²,Wang Jianhong¹,Xu Limei²,Xu Xiao²,Ouyang Kan²,Zhang Hao³⁴,Lu Jianping¹,Duan Li²,Xia Jiang⁵^ORCID

Affiliation:

1. Department of Child and Adolescent Psychiatry, Shenzhen Kangning Hospital, Shenzhen Mental Health Center, Shenzhen 518020, China

2. Department of Orthopedics, the First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen 518035, China

3. State Key Laboratory of Bioelectronics, National Demonstration Center for Experimental Biomedical Engineering Education, Southeast University, Nanjing 210096, Jiangsu, China

4. EVLiXiR Biotech Inc., Nanjing 210032, Jiangsu, China

5. Department of Chemistry, the Chinese University of Hong Kong, Shatin, Hong Kong SAR, China

Abstract

This review summarizes the use of cell-derived vesicles, including EVs and exosomes for the delivery of CRISPR/Cas tools, with a focus on the state-of-the-art engineering strategies to realize efficient cargo packaging and loading.

Funder

Science, Technology and Innovation Commission of Shenzhen Municipality

Basic and Applied Basic Research Foundation of Guangdong Province

Special Project for Research and Development in Key areas of Guangdong Province

Sanming Project of Medicine in Shenzhen

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/BM/D2BM00480A

Reference66 articles.