Unusual topological RNA G-quadruplex formed by an RNA duplex: implications for the dimerization of SARS-CoV-2 RNA-Reference-Cited by-同舟云学术

Unusual topological RNA G-quadruplex formed by an RNA duplex: implications for the dimerization of SARS-CoV-2 RNA

Published:2023 Issue:85 Volume:59 Page:12703-12706
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Wang Shiyu¹,Song Yi¹,He Zhiyong¹,Saneyoshi Hisao¹,Iwakiri Rie¹,Xu Pengyu²,Zhao Chuanqi³^ORCID,Qu Xiaogang³⁴^ORCID,Xu Yan¹^ORCID

Affiliation:

1. Division of Chemistry, Department of Medical Sciences, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan

2. Shonan Laboratory, Corporate R&D Headquarters, Otsuka Chemical Co., Ltd., 2Chome26-1, Muraokahigashi, Fujisawa, Kanagawa 251-8555, Japan

3. Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Science, Changchun, Jilin 130022, P. R. China

4. School of Applied Chemistry and Engineering, University of Science and Technology of China, Hefei, Anhui 230026, P. R. China

Abstract

Two RNA sequences form a duplex and self-associate to form a dimeric G-quadruplex in SARS-COV-2 RNA.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/CC/D3CC03192F

Reference21 articles.

1. Coronavirus biology and replication: implications for SARS-CoV-2

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3. Chemistry in human telomere biology: structure, function and targeting of telomere DNA/RNA

4. An anionic phthalocyanine decreases NRAS expression by breaking down its RNA G-quadruplex

5. Adaptive and Specific Recognition of Telomeric G-Quadruplexes via Polyvalency Induced Unstacking of Binding Units