Effects of maternal high-fat diet on fetal growth, placental nutrient transporters and circular RNA expression profiles

Author:

He Tianle1ORCID,Chen Qingyun1ORCID,Yuan Zhidong2ORCID,Yang Yulian1ORCID,Cao Kai1ORCID,Luo Ju1ORCID,Dong Guozhong1ORCID,Peng Xie1,Yang Zhenguo1

Affiliation:

1. Laboratory for Bio-feed and Molecular Nutrition, College of Animal Science and Technology, Southwest University, Chongqing 400715, China

2. Key Laboratory of Prevention and Treatment of Cardiovascular and Cerebrovascular Diseases, Ministry of Education, Gannan Medical University, Ganzhou 341000, China

Abstract

Maternal high-fat diet can affect intrauterine fetal development by regulating body metabolism. Meanwhile, differentially expressed circRNAs in the placenta during a high-fat diet regulate placental nutrient transport and fetal development in multiple ways.

Funder

National Natural Science Foundation of China

Chongqing Municipal Education Commission Foundation

China Association for Science and Technology

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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