Straightforward access to fluoroalkyl tetrazoles from fluoroalkyl N-sulfonylhydrazones

Author:

Fang Zhongxue1,Zhang Yujie1ORCID,Wang Hongwei2,Zanoni Giuseppe3ORCID,Li Jianxin2,Li Xingqi2,Liu Zhaohong2ORCID,Ning Yongquan2ORCID

Affiliation:

1. School of Chemistry and Environmental Engineering, Yancheng Teachers University, Yancheng City 224007, People's Republic of China

2. Jilin Province Key Laboratory of Organic Functional Molecular Design & Synthesis, Department of Chemistry, Northeast Normal University, Changchun 130024, China

3. Department of Chemistry, University of Pavia, Viale Taramelli 12, Pavia 27100, Italy

Abstract

A metal-free cycloaddition reaction of fluoroalkyl N-sulfonylhydrazones with arene-diazonium salts has been reported. This transformation represents the first general procedure to access mono-, di- and perfluoroalkyl tetrazole products.

Funder

National Natural Science Foundation of China

Department of Science and Technology of Jilin Province

Fundamental Research Funds for the Central Universities

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Reference44 articles.

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3. T.Hiyama and H.Yamamoto , Organofluorine Building Blocks , in Organofluorine Compounds , ed. H. Yamamoto , Springer , Berlin , 2000 , vol. 77

4. Fluorine in Pharmaceuticals: Looking Beyond Intuition

5. Organic fluorine compounds: a great opportunity for enhanced materials properties

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