Diversified synthesis and α-selective glycosylation of 3-amino-2,3,6-trideoxy sugars
Author:
Affiliation:
1. Hubei Key Laboratory of Natural Medicinal Chemistry and Resource Evaluation
2. School of Pharmacy; Huazhong University of Science and Technology
3. Wuhan
4. China
5. Institute of Brain Research
Abstract
Quick access to various unnatural 3-amino-2,3,6-trideoxy sugars was achieved by sequential functionalization of a glycal intermediate. This strategy and the further glycosylation method allowed the efficient late-stage modification of bioactive natural products and drugs.
Funder
National Natural Science Foundation of China
State Key Laboratory of Bio-organic and Natural Products Chemistry
Huazhong University of Science and Technology
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2018/QO/C8QO00948A
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