1,2-cis-Selective glucosylation enabled by halogenated benzyl protecting groups

Author:

Njeri Dancan K.1234,Pertuit Claude J.1234,Ragains Justin R.1234ORCID

Affiliation:

1. Department of Chemistry

2. Louisiana State University

3. Baton Rouge

4. USA

Abstract

Electron-withdrawing groups and Lewis basic solvent enable 1,2-cis-selectivity.

Funder

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference28 articles.

1. R. R. Schmidt and K.-H.Jung , in Carbohydrates in Chemistry and Biology , ed. B. Ernst , G. W. Hart and P. Sinaÿ , 2000 , pp. 5–59

2. Thioglycosides in sequential glycosylation strategies

3. H. A. Chokhawala and X.Chen , Enzymatic Approaches to O-Glycoside Introduction: Glycosyltransferases , in Comprehensive Glycoscience , ed. J. P. Kamerling , Elsevier Ltd. , Oxford , 2007 , vol. 1 , pp. 415–451

4. Synthesis of Complex Carbohydrates and Glycoconjugates:  Enzyme-Based and Programmable One-Pot Strategies

5. A General Strategy for the Chemoenzymatic Synthesis of Asymmetrically Branched N -Glycans

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