Base-promoted addition of DMA with 1,1-diarylethylenes: application to a total synthesis of (−)-sacidumlignan B

Author:

Luo Zhen-Biao1234ORCID,Wang Ya-Wen5234ORCID,Peng Yu1234ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering

2. Lanzhou University

3. Lanzhou 730000

4. China

5. Key Laboratory of Nonferrous Metals Chemistry and Resources Utilization of Gansu Province and College of Chemistry and Chemical Engineering

Abstract

Addition of DMA to 1,1′-diarylethylenes promoted by base has been developed, which results in a new synthetic strategy for (−)-sacidumlignan B.

Funder

National Natural Science Foundation of China

Lanzhou University

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Reference35 articles.

1. State Administration of Traditional Chinese Medicine , in Chinese Herb (Zhonghua Bencao) , Shanghai Science and Technology Press , Shanghai , 1999 , vol. 6 , pp. 383

2. Lignans and Their Degraded Derivatives from Sarcostemma acidum

3. Total Synthesis of (±)-Sacidumlignan D

4. Total Synthesis of (−)-Sacidumlignans B and D

5. Total synthesis of (±)-sacidumlignans D and A through Ueno–Stork radical cyclization reaction

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