A ROS storm generating nanocomposite for enhanced chemodynamic therapy through H<sub>2</sub>O<sub>2</sub> self-supply, GSH depletion and calcium overload-Reference-Cited by-同舟云学术

A ROS storm generating nanocomposite for enhanced chemodynamic therapy through H₂O₂ self-supply, GSH depletion and calcium overload

Published:2024 Issue:17 Volume:16 Page:8479-8494
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Li Yong¹,Wang Jing¹,Zhu Tao¹,Zhan Ying²,Tang Xiaoli¹,Xi Jianying¹,Zhu Xiaohui¹^ORCID,Zhang Yong³^ORCID,Liu Jinliang¹^ORCID

Affiliation:

1. School of Environmental and Chemical Engineering, Shanghai University, Shanghai, China, 200444

2. School of Life Science, Shanghai University, Shanghai, China, 200444

3. Department of Biomedical Engineering, City University of Hong Kong, 83 Tat Chee Avenue, Kowloon, Hong Kong

Abstract

A CaO2-based multifunctional nanocomposite which possesses H2O2 self-supplying, GSH depletion and calcium overload properties was prepared, the nanocomposite can enhance the efficacy of CDT and accelerate tumor apoptosis.

Funder

Natural Science Foundation of Shanghai

National Natural Science Foundation of China

Innovative Research Team of High-level Local University in Shanghai

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/NR/D3NR06422K

Reference58 articles.

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