Differentiating sepsis from non-infectious systemic inflammation based on microvesicle-bacteria aggregation-Reference-Cited by-同舟云学术

Differentiating sepsis from non-infectious systemic inflammation based on microvesicle-bacteria aggregation

Published:2015 Issue:32 Volume:7 Page:13511-13520
ISSN:2040-3364
Container-title:Nanoscale
language:en
Short-container-title:Nanoscale

Author:

Herrmann I. K.¹²³⁴,Bertazzo S.¹²³⁴,O'Callaghan D. J. P.⁵⁶⁷³⁸,Schlegel A. A.⁹¹⁰¹¹¹²,Kallepitis C.¹²³⁴,Antcliffe D. B.⁵⁶⁷³⁸,Gordon A. C.⁵⁶⁷³⁸,Stevens M. M.¹²³⁴

Affiliation:

1. Department of Materials

2. Department of Bioengineering and Institute of Biomedical Engineering

3. Imperial College London

4. London, UK

5. Anaesthetics

6. Pain Medicine and Intensive Care

7. Department of Surgery and Cancer

8. Charing Cross Hospital

9. Swiss HPB and Transplantation Center

10. Department of Surgery

11. University Hospital Zurich

12. CH-8091 Zurich, Switzerland

Abstract

Sepsis is a leading cause of hospital mortality. Prompt diagnosis has a major impact on patient outcome. Here, we present an assay to rapidly differentiate sepsis from noninfectious inflammation.

Funder

Engineering and Physical Sciences Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science

Link

http://pubs.rsc.org/en/content/articlepdf/2015/NR/C5NR01851J

Reference28 articles.

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3. The enigma of sepsis

4. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care

5. Sepsis biomarkers in unselected patients on admission to intensive or high-dependency care

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