Surface functionalization of extracellular vesicle nanoparticles with antibodies: a first study on the protein corona “variable”

Author:

Musicò Angelo12,Zenatelli Rossella12ORCID,Romano Miriam12,Zendrini Andrea12,Alacqua Silvia12,Tassoni Selene1,Paolini Lucia23,Urbinati Chiara1,Rusnati Marco1,Bergese Paolo124ORCID,Pomarico Giuseppe12ORCID,Radeghieri Annalisa12ORCID

Affiliation:

1. Department of Molecular and Translational Medicine, University of Brescia, Viale Europa 11, 25123 Brescia, Italy

2. CSGI, Center for Colloid and Surface Science, 50019 Florence, Italy

3. Department of Medical and Surgical Specialties, Radiological Sciences and Public Health, University of Brescia, 25123 Brescia, Italy

4. National Center for Gene Therapy and Drugs Based on RNA Technology – CN3, Padova, Italy

Abstract

Comparison between two edge cases of EVs modified with Cetuximab by chemisorption and physisorption methods: a first exploration of the protein corona “variable”.

Funder

H2020 Future and Emerging Technologies

Ministero dell’Istruzione, dell’Università e della Ricerca

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Materials Science,General Chemistry,Atomic and Molecular Physics, and Optics,Bioengineering

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