Development of anti-HBV agents targeting HBV capsid proteins-Reference-Cited by-同舟云学术

Development of anti-HBV agents targeting HBV capsid proteins

Published:2023 Issue:10 Volume:14 Page:1973-1980
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Kobayakawa Takuya¹^ORCID,Amano Masayuki²³^ORCID,Nakayama Miyuki¹,Tsuji Kohei¹^ORCID,Ishii Takahiro¹^ORCID,Miura Yutaro¹,Shinohara Kouki¹,Yamamoto Kenichi¹,Matsuoka Masao³,Tamamura Hirokazu¹^ORCID

Affiliation:

1. Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University (TMDU), 2-3-10 Kandasurugadai, Chiyoda-ku, Tokyo 101-0062, Japan

2. Department of Clinical Retrovirology, Joint Research Center for Human Retrovirus Infection, Kumamoto and Kagoshima Universities, Kumamoto 860-0811, Japan

3. Department of Hematology, Rheumatology, and Infectious Diseases, Faculty of Life Sciences, Kumamoto University, Kumamoto 860-8556, Japan

Abstract

>Design and synthesis of anti-hepatitis B virus (HBV) agents: A small anti-HBV compound, Cpd4 (1), was identified by in silico screening. Its structure–activity relationship studies discovered a more potent derivative, TKB-HBV-CA-001 (3b).

Funder

Japan Agency for Medical Research and Development

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/MD/D3MD00258F

Reference22 articles.

1. Therapeutic strategies for hepatitis B virus infection: towards a cure

2. Hepatitis B

3. Hepatitis B Therapeutic Vaccine: A Patent Review

4. WHO , Hepatitis B , 2022 , https://www.who.int/news-room/fact-sheets/detail/hepatitis-b , (accessed May 11, 2023)

5. A. J.Zuckerman , Hepatitis Viruses, in Medical Microbiology , ed. S. Baron , University of Texas Medical Branch at Galveston , Galveston (TX) , 4th edn, 1996 , ch. 70

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