Naringenin mitigates thioacetamide-induced hepatic encephalopathy in rats: targeting the JNK/Bax/caspase-8 apoptotic pathway-Reference-Cited by-同舟云学术

Naringenin mitigates thioacetamide-induced hepatic encephalopathy in rats: targeting the JNK/Bax/caspase-8 apoptotic pathway

Published:2023 Issue:2 Volume:14 Page:1248-1258
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Eraky Salma M.¹,El-Kashef Dalia H.²^ORCID,El-Sherbiny Mohamed³⁴,Abo El-Magd Nada F.¹^ORCID

Affiliation:

1. Biochemistry Department, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt

2. Department of Pharmacology and Toxicology, Faculty of Pharmacy, Mansoura University, Mansoura 35516, Egypt

3. Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, P.O. Box 71666, Riyadh, 11597, Saudi Arabia

4. Department of Anatomy, Faculty of Medicine, Mansoura, Egypt

Abstract

The proposed mechanism of naringenin (NGN) in reversing thioacetamide inducing hepatic encephalopathy through its anti-apoptotic properties through upregulation of pro-BDNF, BDNF and down-regulation of cJNK/Bax/caspase-8 pathway.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D2FO03470K

Reference52 articles.

1. Inhalation of volatile anesthetics via a laryngeal mask is associated with lower incidence of intraoperative awareness in non-critically ill patients

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