Solvatomorph and polymorph screening of clopamide drug and its copper(ii) complex crystals

Author:

Gál G. Tamás1,May Nóra V.1ORCID,Trif László2ORCID,Mihály Judith2,Bombicz Petra1ORCID

Affiliation:

1. Centre for Structural Science, Research Centre for Natural Sciences, Magyar Tudósok Körútja 2, H-1117 Budapest, Hungary

2. Institute of Material and Environmental Chemistry, Research Centre for Natural Sciences, 1117 Magyar Tudósok Körútja 2, Budapest, Hungary

Abstract

The anhydrate and hemihydrate structures of the marketed drug, clopamide, are described the first time. Structural landscape of its copper complexes is presented: three polymorphic modifications and an isostructural series of its alcohol clathrates.

Funder

National Research, Development and Innovation Office

Publisher

Royal Society of Chemistry (RSC)

Subject

Condensed Matter Physics,General Materials Science,General Chemistry

Reference33 articles.

1. Polymorph Impact on the Bioavailability and Stability of Poorly Soluble Drugs

2. Dealing with the Impact of Ritonavir Polymorphs on the Late Stages of Bulk Drug Process Development

3. J. M.Miller , N.Rodríguez-Hornedo , A. C.Blackburn , D.Macikenas and B. M.Collman , Solvent Systems for Crystallization and Polymorph Selection, Part of the Biotechnology: Pharmaceutical Aspects book series , Springer Nature Switzerland AG , 2007 , pp. 53–109

4. Polymorphism Solvatomorphism 2008

5. Clopamide: Plasma concentrations and diuretic effect in humans

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