Phenothiazine-linked nucleosides and nucleotides for redox labelling of DNA
Author:
Affiliation:
1. Institute of Organic Chemistry and Biochemistry
2. Czech Academy of Sciences
3. CZ-16610 Prague 6
4. Czech Republic
5. Institute of Biophysics
6. 612 65 Brno
7. Central European Institute of Technology
8. Department of Organic Chemistry
Abstract
New phenothiazine-modified nucleotides were prepared and used for enzymatic synthesis of labelled DNA for electrochemical detection and redox coding of DNA bases.
Funder
Akademie ved Ceské Republiky
Czech Science Foundation
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB01439B
Reference38 articles.
1. Electrochemistry of Nucleic Acids
2. Nucleobase modification as redox DNA labelling for electrochemical detection
3. Multipotential Electrochemical Detection of Primer Extension Reactions on DNA Self-Assembled Monolayers
4. Ferrocenylethynyl Derivatives of Nucleoside Triphosphates: Synthesis, Incorporation, Electrochemistry, and Bioanalytical Applications
5. Aminophenyl- and Nitrophenyl-Labeled Nucleoside Triphosphates: Synthesis, Enzymatic Incorporation, and Electrochemical Detection
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