Polymersome-based protein drug delivery – quo vadis?

Author:

Gouveia Micael G.1ORCID,Wesseler Justus P.1ORCID,Ramaekers Jobbe1,Weder Christoph2ORCID,Scholten Philip B. V.2ORCID,Bruns Nico13ORCID

Affiliation:

1. Department of Pure and Applied Chemistry, University of Strathclyde, Thomas Graham Building, 295 Cathedral Street, Glasgow G1 1XL, UK

2. Adolphe Merkle Institute, Chemin des Verdiers 4, 1700 Fribourg, Switzerland

3. Department of Chemistry, Technical University of Darmstadt, Alarich-Weiss-Straße 4, 64287 Darmstadt, Germany

Abstract

Block copolymer vesicles are well suited as nano-sized drug delivery vehicles for therapeutic proteins. However, they have not reached the clinic yet. Why? The review discusses opportunities and obstacles of polymersome-based protein drug delivery.

Funder

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

H2020 Marie Skłodowska-Curie Actions

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

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