Ring-locking strategy facilitating determination of absolute optical purity of 2-amino-1-butanol by reverse-phase high-performance liquid chromatography
Author:
Affiliation:
1. Beijing Key Laboratory of Active Substances Discovery and Druggability Evaluation
2. Institute of Materia Medica
3. Chinese Academy of Medical Sciences
4. Peking Union Medical College
5. Beijing 100050
Abstract
A concise and efficient reverse-phase high-performance liquid chromatography (RPLC) method has been established for absolute optical purity assay of 2-amino-1-butanol, which is an important synthetic intermediate of various drugs.
Funder
CAMS
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2017/RA/C7RA09362D
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