Metal free C–O bond cleavage: a new strategy for the synthesis of substituted oxazoles-Reference-Cited by-同舟云学术

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Metal free C–O bond cleavage: a new strategy for the synthesis of substituted oxazoles

Published:2024 Issue:38 Volume:14 Page:28210-28214
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Li Shengwang¹,Liu Guiqin¹,Zhang Zheyan¹,Chen Ruiling²,Tian Haiying²,Wang Huifeng¹,Chen Xiuling¹^ORCID

Affiliation:

1. Hubei Key Laboratory of Radiation Chemistry and Functional Materials, Hubei University of Science and Technology, Xianning 437100, China

2. School of Pharmacy, Changzhi Medical College, Changzhi, 046000, China

Abstract

A strategy for C–O bond cleavage of ester for the synthesis of substituted oxazoles was developed. The synthesis proceeded smoothly under metal-free conditions, combining C–O bond cleavage, C–N and C–O bond formation in one pot.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA05122J

Reference45 articles.

1. Metal-catalyzed activation of ethers via C–O bond cleavage: a new strategy for molecular diversity

2. Exploration of Earth-Abundant Transition Metals (Fe, Co, and Ni) as Catalysts in Unreactive Chemical Bond Activations

3. Stereospecific Nickel-Catalyzed Cross-Coupling Reactions of Benzylic Ethers and Esters

4. Nickel-Catalyzed CO/CH Cross-Coupling Reactions for CC Bond Formation

5. Platinum(ii)-catalyzed dehydrative C3-benzylation of electron-deficient indoles with benzyl alcohols

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