A near IR photosensitizer based on self-assembled CdSe quantum dot-aza-BODIPY conjugate coated with poly(ethylene glycol) and folic acid for concurrent fluorescence imaging and photodynamic therapy

Author:

Yan Yu12345,Tian Jiangwei678910,Hu Fengrui111241314,Wang Xiaoyong111241314,Shen Zhen12345

Affiliation:

1. State Key Laboratory of Coordination Chemistry

2. Collaborative Innovation Center of Advanced Microstructures

3. School of Chemistry and Chemical Engineering

4. Nanjing University

5. Nanjing 210046

6. State Key Laboratory of Natural Medicines

7. Jiangsu Key Laboratory of TCM Evaluation and Translational Research

8. Department of Complex Prescription of TCM

9. China Pharmaceutical University

10. Nanjing 211198

11. Laboratory of Micro/Nano-photonics and Ultrafast Spectroscopy

12. School of Physics

13. Nanjing 210093

14. China

Abstract

Nanocomposite comprised of CdSe quantum dot-thiophene-substituted aza-BODIPY conjugate coated with FA and PEG has been developed for simultaneous fluorescence imaging and photodynamic therapy of HeLa cells via Förster resonance energy transfer.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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