Near infrared fluorescence-magnetic resonance dual-modal imaging with Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles-Reference-Cited by-同舟云学术

Near infrared fluorescence-magnetic resonance dual-modal imaging with Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles

Published:2016 Issue:1 Volume:8 Page:214-221
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Gao Ai¹²³⁴⁵,Zhang Dan¹²³⁴⁵,Yin Xue-Bo¹²³⁴⁵

Affiliation:

1. Research Center for Analytical Sciences

2. College of Chemistry

3. Nankai University

4. State Key Laboratory of Medicinal Chemical Biology

5. Tianjin Key Laboratory of Biosensing and Molecular Recognition

Abstract

We report a reliable and facile procedure to prepare near infrared fluorescence (NIRF)-magnetic resonance dual-modal imaging probes (DMIPs) using Cy5-labeled, Gd–Al co-doped mesoporous silica nanoparticles. High intensity NIRF and a relaxation rate (17.7 mM⁻¹s⁻¹) can be observed. Furthermore, the DMIPs in saline were injected into mice through the tail vein for imaging.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2016/AY/C5AY02230D

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