Development of a new experimental NMR strategy for covalent cysteine protease inhibitors screening: toward enhanced drug discovery-Reference-Cited by-同舟云学术

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Development of a new experimental NMR strategy for covalent cysteine protease inhibitors screening: toward enhanced drug discovery

Published:2024 Issue:37 Volume:14 Page:26829-26836
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Chihab Abdelali¹,El Brahmi Nabil¹,Hamdoun Ghanem¹,El Abbouchi Abdelmoula¹,Ghammaz Hamza²,Touil Nadia³,Bousmina Mostafa¹,El Fahime Elmostafa²,El Kazzouli Saïd¹^ORCID

Affiliation:

1. Euromed University of Fes, UEMF, Morocco

2. Centre National de la Recherche Scientifique et Technique (CNRST), Angle avenues des FAR et Allal El Fassi, Hay Ryad, 10102 Rabat, Morocco

3. Cell Culture Unit, Center of Virology, Infectious, and Tropical Diseases, Mohammed V Military Hospital, Rabat, Morocco

Abstract

In the development of antiviral drugs, proteases and polymerases are among the most important targets.

Funder

Université Euromed de Fès

Publisher

Royal Society of Chemistry (RSC)

Link

http://pubs.rsc.org/en/content/articlepdf/2024/RA/D4RA04938A

Reference38 articles.

1. Cysteine Proteases: Modes of Activation and Future Prospects as Pharmacological Targets

2. Proteases: Multifunctional Enzymes in Life and Disease

3. Molecular and Biotechnological Aspects of Microbial Proteases

4. Cysteine proteases: Battling pathogenic parasitic protozoans with omnipresent enzymes

5. Cathepsin cysteine proteases in cardiovascular disease

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