Water-soluble amphiphilic ruthenium(ii) polypyridyl complexes as potential light-activated therapeutic agents-Reference-Cited by-同舟云学术

Water-soluble amphiphilic ruthenium(ii) polypyridyl complexes as potential light-activated therapeutic agents

Published:2020 Issue:65 Volume:56 Page:9332-9335
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Estalayo-Adrián Sandra¹²³⁴⁵^ORCID,Blasco Salvador¹²³⁴⁵^ORCID,Bright Sandra A.⁶⁷²³⁴,McManus Gavin J.⁶⁷²³⁴,Orellana Guillermo⁸⁹¹⁰¹¹^ORCID,Williams D. Clive⁶⁷²³⁴,Kelly John M.¹²³⁴⁵^ORCID,Gunnlaugsson Thorfinnur¹²³⁴⁵^ORCID

Affiliation:

1. School of Chemistry and Trinity Biomedical Sciences Institute (TBSI)

2. Trinity College Dublin

3. The University of Dublin

4. Dublin 2

5. Ireland

6. School of Biochemistry and Immunology

7. Trinity Biomedical Sciences Institute (TBSI)

8. Department of Organic Chemistry

9. Faculty of Chemistry, Universidad Complutense de Madrid

10. E-28040 Madrid

11. Spain

Abstract

Two new water-soluble amphiphilic Ru(ii) polypyridyl complexes were synthesised and their photophysical and photobiological properties evaluated; both complexes showed a rapid cellular uptake and phototoxicity against HeLa cervical cancer cells.

Funder

Science Foundation Ireland

H2020 Marie Skłodowska-Curie Actions

Trinity College Dublin

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2020/CC/D0CC04397D

Reference50 articles.

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4. Mechanisms of action of Ru(ii) polypyridyl complexes in living cells upon light irradiation

5. Transition Metal Complexes and Photodynamic Therapy from a Tumor-Centered Approach: Challenges, Opportunities, and Highlights from the Development of TLD1433

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