Modification of the antigenicity of cancer cells by conjugates consisting of hyaluronic acid and foreign antigens

Author:

Ogata Soichi1,Tsuji Reika1,Moritaka Atsushi1,Ito Shoya1,Mochizuki Shinichi1ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, The University of Kitakyushu, 1-1 Hibikino, Wakamatsu-ku, Kitakyushu, Fukuoka 808-0135, Japan

Abstract

Hyaluronic acid (HA) delivers conjugated foreign antigens to cancer cells, resulting in changing the presenting antigens on MHC class I molecules from self-antigens to foreign antigens.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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