A Cu-BOX catalysed enantioselective Mukaiyama-aldol reaction with difluorinated silyl enol ethers and acylpyridine <i>N</i>-oxides-Reference-Cited by-同舟云学术

A Cu-BOX catalysed enantioselective Mukaiyama-aldol reaction with difluorinated silyl enol ethers and acylpyridine N-oxides

Published:2023 Issue:2 Volume:21 Page:345-350
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Sanz-Marco Amparo¹^ORCID,Esperilla Daniel¹,Montesinos-Magraner Marc¹^ORCID,Vila Carlos¹^ORCID,Muñoz M. Carmen²^ORCID,Pedro José R.¹^ORCID,Blay Gonzalo¹^ORCID

Affiliation:

1. Departament de Química Orgànica-Facultat de Química, Universitat de València, C/Dr. Moliner 50, 46100-Burjassot, València, Spain

2. Departament de Física Aplicada, Universitat Politècnica de València, C/Cami de Vera s/n, 46022-València, Spain

Abstract

Chiral difluorinated tertiary alcohols are obtained in moderate to excellent yields and high enantioselectivities upon a Cu(ii)-catalysed reaction of difluorinated silyl enol ethers and acylpyridine N-oxides.

Funder

Conselleria de Innovación, Universidades, Ciencia y Sociedad Digital, Generalitat Valenciana

Agencia Estatal de Investigación

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/OB/D2OB01763F

Reference78 articles.

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