A unimolecular theranostic system with H2O2-specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells-Reference-Cited by-同舟云学术

A unimolecular theranostic system with H2O2-specific response and AIE-activity for doxorubicin releasing and real-time tracking in living cells

Published:2018 Issue:20 Volume:8 Page:10975-10979
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Gao Xiaoying¹²³⁴⁵,Cao Jie¹²³⁴⁵,Song Yinuo¹²³⁴⁵,Shu Xiao¹²³⁴⁵,Liu Jianzhao¹²³⁴⁵,Sun Jing Zhi¹²³⁴⁵^ORCID,Liu Bin⁶⁷⁸⁸^ORCID,Tang Ben Zhong¹²³⁴⁵

Affiliation:

1. MOE Key Laboratory of Macromolecular Synthesis and Functionalization

2. Department of Polymer Science and Engineering

3. Zhejiang University

4. Hangzhou 310027

5. China

6. Department of Chemical and Biomolecular Engineering

7. National University of Singapore

8. Singapore

Abstract

A theranostic drug delivery system composed of tetraphenylethene (AIE-gen), benzyl-boronic ester (trigger) and doxorubicin (drug) was synthesized and its functions in cell imaging, drug delivery tracking, and therapeutic effect were evaluated.

Funder

National Natural Science Foundation of China

Innovation and Technology Commission

National University of Singapore

Ministry of Science and Technology of the People's Republic of China

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA01185K

Reference29 articles.

1. Human Cancer Classification: A Systems Biology- Based Model Integrating Morphology, Cancer Stem Cells, Proteomics, and Genomics

2. Cancer's Molecular Sweet Tooth and the Warburg Effect: Figure 1.

3. Nanocarriers as an emerging platform for cancer therapy

4. Responsive Theranostic Systems: Integration of Diagnostic Imaging Agents and Responsive Controlled Release Drug Delivery Carriers

5. Spatiotemporal Drug Release Visualized through a Drug Delivery System with Tunable Aggregation-Induced Emission

Cited by 27 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Boronate-based bioactive compounds activated by peroxynitrite and hydrogen peroxide;Redox Biochemistry and Chemistry;2024-12

2. Prodrug-conjugated tumor-seeking commensals for targeted cancer therapy;Nature Communications;2024-05-21

3. Theranostic applications of biomolecule‐responsive aggregation‐induced emission luminogens;Interdisciplinary Medicine;2023-09-11

4. Aggregation‐induced emission polymers via reversible‐deactivation radical polymerization;Aggregate;2023-09-06

5. Coumarin-Based Fluorescent Inhibitors for Photocontrollable Bioactivation;Molecular Pharmaceutics;2023-04-27