Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation-Reference-Cited by-同舟云学术

Tannic acid directly targets pyruvate kinase isoenzyme M2 to attenuate colon cancer cell proliferation

Published:2018 Issue:11 Volume:9 Page:5547-5559
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Yang Peng¹²³⁴⁵,Ding Guo-Bin¹²³⁴⁵^ORCID,Liu Wen¹²³⁴⁵,Fu Rong¹²³⁴⁵,Sajid Amin¹²³⁴⁵,Li Zhuoyu¹²³⁴⁵^ORCID

Affiliation:

1. Institute of Biotechnology

2. Key Laboratory of Chemical Biology and Molecular Engineering of National Ministry of Education

3. Shanxi University

4. Taiyuan 030006

5. China

Abstract

Tannic acid, which ubiquitously exists in grapes and green tea, binds to K433 to trigger dissociation of PKM2 tetramers and further block the metabolic activity of PKM2 to suppress colorectal cancer cell proliferation.

Funder

National Natural Science Foundation of China

Shanxi Province Science Foundation for Youths

Shanxi University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO01161C

Reference44 articles.

1. Cancer statistics, 2012

2. Inhibitory effects of tannic acid on fatty acid synthase and 3T3-L1 preadipocyte

3. Amelioration of 1,2 Dimethylhydrazine (DMH) Induced Colon Oxidative Stress, Inflammation and Tumor Promotion Response by Tannic Acid in Wistar Rats

4. Apoptotic effect of tannic acid on fatty acid synthase over-expressed human breast cancer cells

5. Tannic Acid Inhibits Proliferation, Migration, Invasion of Prostate Cancer and Modulates Drug Metabolizing and Antioxidant Enzymes

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