Anti-GPC1-modified mesoporous silica nanoparticles as nanocarriers for combination therapy and targeting of PANC-1 cells-Reference-Cited by-同舟云学术

Anti-GPC1-modified mesoporous silica nanoparticles as nanocarriers for combination therapy and targeting of PANC-1 cells

Published:2021 Issue:15 Volume:2 Page:5224-5235
ISSN:2633-5409
Container-title:Materials Advances
language:en
Short-container-title:Mater. Adv.

Author:

Estevão Bianca Martins¹²³⁴^ORCID,Comparetti Edson José¹²³⁴,Rissi Nathalia Cristina¹²³⁴,Zucolotto Valtencir¹²³⁴^ORCID

Affiliation:

1. Nanomedicine and Nanotoxicology Group

2. São Carlos Institute of Physics–University of São Paulo

3. São Carlos

4. Brazil

Abstract

We present a novel therapeutic nanoplatform based on mesoporous silica nanoparticles encapsulating ferulic acid/gemcitabine and functionalized with anti-GPC1 antibodies to target human pancreatic cancer (PANC-1) cells.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Fundação de Amparo à Pesquisa do Estado de São Paulo

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MA/D1MA00225B

Reference70 articles.

1. Pancreatic cancer

2. Clinical applications of circulating tumor DNA and circulating tumor cells in pancreatic cancer

3. Gemcitabine Combination Nano Therapies for Pancreatic Cancer

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