Improved survival rate and minimal side effects of doxorubicin for lung metastasis using engineered discoidal polymeric particles

Author:

Park Sanghyo1,Park Hyungkyu1,Park Chaewon1,Yun Wan Su23,Hwang Soonjae45,Yoon Hong Yeol23,Kwon Ick Chan23,Kim Kwangmeyung23ORCID,Key Jaehong1ORCID

Affiliation:

1. Department of Biomedical Engineering, Yonsei University, Wonju 26493, Republic of Korea

2. KU-KIST Graduate School of Converging Science and Technology, Korea University, Seoul 02841, Republic of Korea

3. Center for Theragnosis, Biomedical Research Institute, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea

4. Department of Biochemistry, Lee Gil Ya Cancer and Diabetes Institute, College of Medicine, Gachon University, Incheon 21999, Korea

5. Department of Biomedical Laboratory Science, Yonsei University, Wonju 26493, Republic of Korea

Abstract

Schematic illustration of the synthesis of DOX-DPPs. Improving the therapeutic effect of lung cancer requires the development of a drug delivery system that is intensively delivered to the lungs and effective release of the drug from its location.

Funder

National Research Foundation of Korea

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

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