Gastrointestinal absorption, antiproliferative and anti-inflammatory effect of the major carotenoids of Gardenia jasminoides Ellis on cancer cells

Author:

Oliveira Hélder12345,Cai Xiaoshuang6789,Zhang Qian6789,de Freitas Victor12345,Mateus Nuno12345,He Jingren678910,Fernandes Iva12345ORCID

Affiliation:

1. REQUIMTE/LAQV

2. Department of Chemistry and Biochemistry

3. Faculty of Sciences

4. University of Porto

5. 4169-007 Porto

6. School of Food Science and Engineering

7. Wuhan Polytechnic University

8. Wuhan

9. China

10. Hubei Collaborative Innovation Center for Processing of Agricultural Products

Abstract

Crocetin was the carotenoid with the highest gastrointestinal transport efficiency and the most effective in inhibiting cancer cell proliferation. In addition, this carotenoid showed involvement in the downregulation of the inflammatory cytokines.

Funder

Natural Science Foundation of Hubei Province

Fundação para a Ciência e a Tecnologia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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