Hidden symmetry of the flavivirus protein shell and pH-controlled reconstruction of the viral surface-Reference-Cited by-同舟云学术

Hidden symmetry of the flavivirus protein shell and pH-controlled reconstruction of the viral surface

Published:2023 Issue:1 Volume:11 Page:225-234
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Konevtsova Olga V.¹,Golushko Ivan Yu.¹,Podgornik Rudolf²³⁴,Rochal Sergei B.¹^ORCID

Affiliation:

1. Physics Faculty, Southern Federal University, Rostov-on-Don, Russia

2. School of Physical Sciences and Kavli Institute for Theoretical Sciences, University of Chinese Academy of Sciences, Beijing 100049, China

3. CAS Key Laboratory of Soft Matter Physics, Institute of Physics, Chinese Academy of Sciences, Beijing 100190, China

4. Wenzhou Institute of the University of Chinese Academy of Sciences, Wenzhou, Zhejiang 325000, China

Abstract

A pH-induced change in the charge distribution of proteins leads to a structural transformation of the outer flavivirus shell, which violates the hidden symmetry of the mutual arrangement of proteins located on opposite sides of the lipid membrane.

Funder

Russian Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2023/BM/D2BM01562E

Reference69 articles.

1. ICTV Report Chapters|ICTV, https://ictv.global/report

2. Phylogeny of the Genus Flavivirus

3. The global distribution and burden of dengue

4. Recent update on anti-dengue drug discovery

5. Recent advances in antiviral drug development towards dengue virus

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