7-Azaspiroketal as a unique and effective auxochrome moiety: demonstration in a fluorescent coumarin dye and application in cell imaging-Reference-Cited by-同舟云学术

7-Azaspiroketal as a unique and effective auxochrome moiety: demonstration in a fluorescent coumarin dye and application in cell imaging

Published:2023 Issue:47 Volume:47 Page:21608-21611
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Indurthi Harish K.¹,Goswami Pooja²,Das Samarpita¹^ORCID,Saha Pallavi¹^ORCID,Koch Biplob²,Sharma Deepak K.¹^ORCID

Affiliation:

1. Department of Pharmaceutical Engg. And Tech., IIT-Banaras Hindu University, Varanasi, 221005, UP, India

2. Genotoxicology and Cancer Biology Laboratory, Department of Zoology Institute of Science, Banaras Hindu University, Varanasi, UP, 221005, India

Abstract

A new type of fluorescent coumarin dye was synthesized using 7-azaspiroketals as the electron-donating auxochrome group. Such modifications resulted in high-quality coumarin fluorophores with improved solubility and brightness.

Funder

Department of Biotechnology, Ministry of Science and Technology, India

Banaras Hindu University

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ04934E

Reference18 articles.

1. Synthesis of 7-Aminocoumarin by Buchwald-Hartwig Cross Coupling for Specific Protein Labeling in Living Cells

2. Bright Ideas for Chemical Biology

3. Bright Building Blocks for Chemical Biology

4. Coumarinylmethyl Caging Groups with Redshifted Absorption

5. Evidence for the TICT mediated nonradiative deexcitation process for the excited coumarin-1 dye in high polarity protic solvents

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