Targeted delivery of a novel peptide–docetaxel conjugate to MCF-7 cells through neuropilin-1 receptor: reduced toxicity and enhanced efficacy of docetaxel-Reference-Cited by-同舟云学术

Targeted delivery of a novel peptide–docetaxel conjugate to MCF-7 cells through neuropilin-1 receptor: reduced toxicity and enhanced efficacy of docetaxel

Published:2015 Issue:112 Volume:5 Page:92596-92601
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Saha Abhijit¹²³⁴,Mohapatra Saswat⁵⁶⁷⁴,Kurkute Prashant¹²³⁴,Jana Batakrishna¹²³⁴,Sarkar Jayita¹²³⁴,Mondal Prasenjit⁵⁶⁷⁴,Ghosh Surajit¹²³⁴⁵

Affiliation:

1. Organic & Medicinal Chemistry Division

2. CSIR-Indian Institute of Chemical Biology

3. Kolkata-700032

4. India

5. Academy of Scientific and Innovative Research (AcSIR)

6. CSIR-Indian Institute of Chemical Biology Campus

7. Kolkata 700 032

Abstract

A novel peptide docetaxel conjugate selectively kills NRP-1 overexpressing breast cancer cells, enhances anticancer activity of docetaxel without affecting the NRP-1 negative cells.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA16741H

Reference30 articles.

1. Specialization of tumour vasculature

2. Drug targeting to specific vascular sites

3. Targeting of drugs and nanoparticles to tumors

4. G. I. Georg , T. C.Boge, Z. S.Cheruvallath, J. S.Clowers, G. C. B.Harriman, M.Hepperle and H.Park, TAXOL®: Science and Applications, CRC Press, New York, 1995, pp. 317–378

5. G. I. Georg , G. C. B.Harriman, D. G.Vander Velde, T. C.Boge, Z. S.Cheruvallath, A.Datta, M.Hepperle, H.Park, R. H.Himes and L.Jayasinghe, Taxane Anticancer Agents: Basic Science and Current Status, American Chemical Society, Washington DC, 1995, pp. 217–231

Cited by 12 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Selective Delivery of Clinically Approved Tubulin Binding Agents through Covalent Conjugation to an Active Targeting Moiety;Current Medicinal Chemistry;2022-09

2. Receptor-Targeting Drug and Drug Carrier for Enhanced Killing Efficacy against Non-Muscle-Invasive Bladder Cancer;ACS Applied Bio Materials;2019-08-19

3. Peptide Blocking of PD-1/PD-L1 Interaction for Cancer Immunotherapy;Cancer Immunology Research;2017-12-07

4. LyP-1-conjugated Fe3O4nanoparticles suppress tumor growth by magnetic induction hyperthermia;Journal of Biomaterials Science, Polymer Edition;2017-11-28

5. Rab11 and Lysotracker Markers Reveal Correlation between Endosomal Pathways and Transfection Efficiency of Surface-Functionalized Cationic Liposome–DNA Nanoparticles;The Journal of Physical Chemistry B;2016-06-03