A PLA-tPU based magnesium ion incorporated CSH/nHA bioactive porous composite scaffold for critical bone defect repair

Author:

Shi Zhi1,Huang Guobin2,Li Zhongming3,Lou Zhenkai1,Gong Zhiqiang1,Wang Xin4,Li Chengyong4,Wang Bing1ORCID

Affiliation:

1. Department of Orthopedics, First Affiliated Hospital of Kunming Medical University, Kunming Medical University, Kunming, Yunnan, 650032, P. R. China

2. Yunnan Key Laboratory of Stomatology and Department of Dental Research, The Affiliated Stomatology Hospital of Kunming Medical University, Kunming, Yunnan 650500, P. R. China

3. Yunnan Provincial Key Laboratory of Energy Saving in Phosphorus Chemical Engineering and New Phosphorus Materials The Higher Educational Key Laboratory for Phosphorus Chemical Engineering of Yunnan Province Faculty of Chemical Engineering Kunming University of Science and Technology, Kunming, Yunnan, 650500, P. R. China

4. Spinal Surgery, The Affiliated Hospital of Yunnan University, Yunnan University, Kunming, Yunnan, 650021, P. R. China

Abstract

This study use freeze-drying technology prepared a PT-M-CN bioactive porous composite scaffold for bone defects repairing. Results showed it has a great potential to promote osteogenic differentiation and new bone regeneration.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Chemistry (miscellaneous)

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