A biocatalytic method for the chemoselective aerobic oxidation of aldehydes to carboxylic acids

Author:

Knaus Tanja1234ORCID,Tseliou Vasilis1234ORCID,Humphreys Luke D.567,Scrutton Nigel S.8910117ORCID,Mutti Francesco G.1234ORCID

Affiliation:

1. Van't Hoff Institute for Molecular Sciences

2. HIMS-Biocat

3. University of Amsterdam

4. The Netherlands

5. GlaxoSmithKline Medicines Research Centre

6. Stevenage

7. UK

8. Manchester Institute of Biotechnology

9. School of Chemistry

10. The University of Manchester

11. Manchester

Abstract

Aldehyde dehydrogenases enable the chemospecific oxidation of structurally diverse aldehydes to carboxylic acids in aqueous environment and using only air.

Funder

H2020 European Research Council

Nederlandse Organisatie voor Wetenschappelijk Onderzoek

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference63 articles.

1. G. Tojo and M.Fernández , Oxidation of Primary Alcohols to Carboxylic Acids, chapter 7: Oxidation of Alcohols to Carboxylic Acids via Isolated Aldehydes , Springer , New York , 2007

2. M. Hudlicky , Oxidations in Organic Chemistry , American Chemical Sociecty , Washington DC , 1990

3. A. H. Hainess , Methods for the Oxidation of Organic Compounds , Academic , New York , 1988

4. 129. Researches on acetylenic compounds. Part XV. The oxidation of primary acetylenic carbinols and glycols

5. A novel chromium trioxide catalyzed oxidation of primary alcohols to the carboxylic acids

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