Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle-Reference-Cited by-同舟云学术

Corynomycolic acid-containing glycolipids signal through the pattern recognition receptor Mincle

Published:2015 Issue:24 Volume:51 Page:5100-5103
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

van der Peet Phillip L.¹²³,Gunawan Christian¹²³,Torigoe Shota⁴⁵⁶⁷⁸,Yamasaki Sho⁴⁵⁶⁷⁸,Williams Spencer J.¹²³

Affiliation:

1. School of Chemistry and Bio21 Molecular Science and Biotechnology Institute

2. University of Melbourne

3. Australia

4. Division of Molecular Immunology

5. Medical Institute of Bioregulation

6. Kyushu University

7. Fukuoka 812-8582

8. Japan

Abstract

Glucose monocorynomycolate is revealed to signal through both mouse and human Mincle. Glycerol monocorynomycolate is shown to selectively signal through human Mincle, with the activity residing predominantly in the 2′S-isomer.

Funder

Japan Society for the Promotion of Science

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2015/CC/C5CC00085H

Reference53 articles.

1. Adaptive Immunity to Fungi

2. C-type lectin receptors orchestrate antifungal immunity

3. MCL and Mincle: C-Type Lectin Receptors That Sense Damaged Self and Pathogen-Associated Molecular Patterns

4. Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

5. Cutting Edge: Mincle Is Essential for Recognition and Adjuvanticity of the Mycobacterial Cord Factor and its Synthetic Analog Trehalose-Dibehenate

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