Diastereoselectivity in the boron aldol reaction of α-alkoxy and α,β-bis-alkoxy methyl ketones-Reference-Cited by-同舟云学术

Diastereoselectivity in the boron aldol reaction of α-alkoxy and α,β-bis-alkoxy methyl ketones

Published:2019 Issue:12 Volume:17 Page:3167-3180
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Fernandes Alessandra A. G.¹²³⁴,Leonarczyk Ives A.⁵⁶⁷⁸⁴,Ferreira Marco A. B.⁵⁶⁷⁸⁴,Dias Luiz Carlos¹²³⁴

Affiliation:

1. Institute of Chemistry

2. University of Campinas

3. Campinas – 13083-970

4. Brazil

5. Centre of Excellence for Research in Sustainable Chemistry (CERSusChem)

6. Department of Chemistry

7. Federal University of São

8. Carlos – 13565-905

Abstract

We investigated the asymmetric induction in boron enolate aldol reactions of α-alkoxy and α,β-bisalkoxy methyl ketones and elucidated the synergistic effect between the stereocenters.

Funder

Conselho Nacional de Desenvolvimento Científico e Tecnológico

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior

Fundação de Amparo à Pesquisa do Estado de São Paulo

GlaxoSmithKline

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/OB/C9OB00358D

Reference40 articles.

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2. A. Abiko , Boron Enolate Chemistry , ACS Symposium Series, 2016 , ch. 4, vol. 1236 , pp. 123–171

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4. The Impact of the Mukaiyama Aldol Reaction in Total Synthesis

5. Exploring the Aldol Reaction in the Synthesis of Bioactive Compounds

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