One pot synthesis of tetrasubstituted thiophenes: [3 + 2] annulation strategy
Author:
Affiliation:
1. Department of Chemistry
2. University of Delhi
3. North Campus
4. Delhi
5. India-110007
6. University of Lucknow
7. Lucknow
8. India-226007
9. Division of SAIF
10. Central Drug Research Institute
11. India-226001
Abstract
A simple, efficient and economical synthesis of dimethyl 3-amino-5-(2-oxo-2-arylethyl)thiophene-2,4-dicarboxylates has been reported by ring opening of methyl 3-amino-6-aryl-4-oxo-4H-thieno[3,2-c]pyran-2-carboxylates by alkoxide ions.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA01290B
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5. Synthesis and Characterization of Novel 2-Amino-3-benzoylthiophene Derivatives as Biased Allosteric Agonists and Modulators of the Adenosine A1 Receptor
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