<i>In vivo</i> bioimaging and detection of endogenous hypochlorous acid in lysosome using a near-infrared fluorescent probe-Reference-Cited by-同舟云学术

In vivo bioimaging and detection of endogenous hypochlorous acid in lysosome using a near-infrared fluorescent probe

Published:2023 Issue:26 Volume:15 Page:3188-3195
ISSN:1759-9660
Container-title:Analytical Methods
language:en
Short-container-title:Anal. Methods

Author:

Jiang Jian¹²,Wang Shaocai³,Wang Sai⁴^ORCID,Yang Yinshuang³,Zhang Xiuli³,Wang Wenjun³,Zhu Xu⁴^ORCID,Fang Mingxi³^ORCID,Xu Yaozeng¹

Affiliation:

1. Department of Orthopaedics, The First Affiliated Hospital of Soochow University, Suzhou 215006, China

2. Department of Orthopaedics, The Affiliated Hospital of Xuzhou Medical University, Xuzhou, China

3. School of Medical Imaging, Xuzhou Medical University, Xuzhou, Jiangsu 221006, P. R. China

4. Jiangsu Key Laboratory of New Drug Research and Clinical Pharmacy, School of Pharmacy, Xuzhou Medical University, Xuzhou, Jiangsu 221004, P. R. China

Abstract

The phagocyte's lysosome is the primary site of hypochlorous acid (HOCl) synthesis, and HOCl can be used as a biomarker for osteoarthritis diagnosis and treatment evaluation.

Funder

Xuzhou Medical University

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/AY/D3AY00338H

Reference30 articles.

1. Chlorinative stress: An under appreciated mediator of neurodegeneration?

2. Genotoxic effects of neutrophils and hypochlorous acid

3. Chemistry and biology of reactive oxygen species in signaling or stress responses