A simple mitochondrial targeting AIEgen for image-guided two-photon excited photodynamic therapy

Author:

Jiang Meijuan12345ORCID,Kwok Ryan T. K.12345,Li Xuesong678910,Gui Chen12345ORCID,Lam Jacky W. Y.12345,Qu Jianan678910,Tang Ben Zhong12345

Affiliation:

1. Department of Chemistry

2. Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and Reconstruction

3. Institute for Advanced Study

4. Institute of Molecular Functional Materials

5. State Key Laboratory of Molecular Neuroscience

6. Department of Electronic and Computer Engineering

7. Center of Systems Biology and Human Health

8. School of Science and Institute for Advanced Study

9. Hong Kong University of Science and Technology

10. Kowloon

Abstract

A simple AIE luminogen, IQ-TPA, with mitochondrial targeting was demonstrated for image-guided two-photon excited photodynamic therapy in cancer cells.

Funder

Innovation and Technology Commission

University Grants Committee

Research Grants Council, University Grants Committee

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

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