Hybrid ligands with calixarene and thiodigalactoside groups: galectin binding and cytotoxicity-Reference-Cited by-同舟云学术

Hybrid ligands with calixarene and thiodigalactoside groups: galectin binding and cytotoxicity

Published:2019 Issue:16 Volume:6 Page:2981-2990
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Zhang Hao¹,Ippel Hans²,Miller Michelle C.³,Wong Tse J.⁴,Griffioen Arjan W.⁴,Mayo Kevin H.³,Pieters Roland J.¹^ORCID

Affiliation:

1. Department of Chemical Biology & Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, P.O. Box 80082, NL-3508 TB Utrecht, The Netherlands

2. Department of Biochemistry and the Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands

3. Department of Biochemistry, Molecular Biology & Biophysics, University of Minnesota, Minneapolis, MN 55455, USA

4. Angiogenesis Laboratory, Amsterdam University Medical Center, location VUMC, Cancer Center Amsterdam, Amsterdam, The Netherlands

Abstract

Galectins have diverse functions and are involved in many biological processes because of their complex intra- and extracellular activities.

Funder

China Scholarship Council

National Institutes of Health

National Science Foundation

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C9QO00810A

Reference51 articles.

1. The -galactomannan Davanat binds galectin-1 at a site different from the conventional galectin carbohydrate binding domain

2. Galectinomics: finding themes in complexity

3. Intracellular functions of galectins

4. Galectins: versatile modulators of cell adhesion, cell proliferation, and cell death

5. Galectins as modulators of tumour progression

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